› 2cu2

X-ray diffraction
2.2Å resolution

Crystal structure of mannose-1-phosphate geranyltransferase from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb2cu2/pdb
PDB entry 2cu2 coloured by chain, front view.
PDB entry 2cu2 coloured by chain, side view.
PDB entry 2cu2 coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Sugahara M, Kunishima N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177877 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleotidyl transferase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 337 amino acids
Theoretical weight: 37.49 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SHI0 (Residues: 1-337; Coverage: 100%)
Gene name: TTHA1750
Sequence domains: Nucleotidyl transferase
Structure domains: Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: I222
Unit cell:
a: 84.128Å b: 91.185Å c: 118.633Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.253
Expression system: Escherichia coli

Quick links