› 2cu7

Solution NMR

Solution structure of the SANT domain of human KIAA1915 protein

Released:
DOI: 10.2210/pdb2cu7/pdb
PDB entry 2cu7 coloured by chain, ensemble of 20 models, front view.
PDB entry 2cu7 coloured by chain, ensemble of 20 models, side view.
PDB entry 2cu7 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional differences of SWIRM domain subtypes.
Yoneyama M, Tochio N, Umehara T, Koshiba S, Inoue M, Yabuki T, Aoki M, Seki E, Matsuda T, Watanabe S, Tomo Y, Nishimura Y, Harada T, Terada T, Shirouzu M, Hayashizaki Y, Ohara O, Tanaka A, Kigawa T, Yokoyama S
J Mol Biol 369 222-38 (2007)
PMID: 17428495

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178438 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deubiquitinase MYSM1 Chain: A
Molecule details ›
Chain: A
Length: 72 amino acids
Theoretical weight: 8.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q5VVJ2 (Residues: 117-181; Coverage: 8%)
Gene names: KIAA1915, MYSM1
Sequence domains: Myb-like DNA-binding domain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

15 review citations

Histone lysine demethylases as targets for anticancer therapy.
Højfeldt et al. (2013)
14 more

3 mentions without citation

Regulation of proteolysis by human deubiquitinating enzymes.
Eletr et al. (2014)
2 more