› 2cu9

X-ray diffraction
1.8Å resolution

Crystal structure of Histone chaperone cia1

Released:
DOI: 10.2210/pdb2cu9/pdb
PDB entry 2cu9 coloured by chain, front view.
PDB entry 2cu9 coloured by chain, side view.
PDB entry 2cu9 coloured by chain, top view.
Source organism: Schizosaccharomyces pombe
Primary publication:
Crystal structures of fission yeast histone chaperone Asf1 complexed with the Hip1 B-domain or the Cac2 C terminus.
Malay AD, Umehara T, Matsubara-Malay K, Padmanabhan B, Yokoyama S
J Biol Chem 283 14022-31 (2008)
PMID: 18334479

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130781 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histone chaperone cia1 Chain: A
Molecule details ›
Chain: A
Length: 161 amino acids
Theoretical weight: 18.35 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli
UniProt:
  • Canonical: O74515 (Residues: 1-161; Coverage: 62%)
Gene names: SPCC663.05c, asf1, cia1
Sequence domains: ASF1 like histone chaperone
Structure domains: Histone chaperone ASF1-like

Ligands and Environments

1 bound ligand:
Ligand PG0 1 x PG0
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: C2
Unit cell:
a: 78.623Å b: 41.297Å c: 67.211Å
α: 90° β: 115.65° γ: 90°
R-values:
R R work R free
0.194 0.191 0.239
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Histone chaperone networks shaping chromatin function.
Hammond et al. (2017)
13 more