› 2cuy

X-ray diffraction
2.1Å resolution

Crystal structure of malonyl CoA-acyl carrier protein transacylase from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb2cuy/pdb
PDB entry 2cuy coloured by chain, front view.
PDB entry 2cuy coloured by chain, side view.
PDB entry 2cuy coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Misaki S, Suzuki K, Kunishima N, Sugawara M, Kuroishi C, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier-protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178134 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Malonyl CoA-acyl carrier protein transacylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 305 amino acids
Theoretical weight: 33.43 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SL77 (Residues: 1-305; Coverage: 100%)
Gene name: TTHA0416
Sequence domains: Acyl transferase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL32B2
Spacegroup: P3221
Unit cell:
a: 121.907Å b: 121.907Å c: 114.916Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.226 0.258
Expression system: Escherichia coli

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