2cvz

X-ray diffraction
1.8Å resolution

Structure of hydroxyisobutyrate dehydrogenase from thermus thermophilus HB8

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-178204 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-hydroxyisobutyrate dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 289 amino acids
Theoretical weight: 31.66 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SLQ6 (Residues: 1-289; Coverage: 100%)
Gene name: TTHA0237
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NDP 3 x NDP
No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P212121
Unit cell:
a: 85.878Å b: 106.367Å c: 168.639Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.182 0.2
Expression system: Escherichia coli BL21(DE3)