2d2z

X-ray diffraction
2.2Å resolution

Crystal structure of Soluble Form Of CLIC4

Released:
Source organism: Homo sapiens
Primary publication:
Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals.
Biochem Biophys Res Commun 343 1272-8 (2006)
PMID: 16581025

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-195347 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chloride intracellular channel protein 4 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 261 amino acids
Theoretical weight: 29.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y696 (Residues: 1-253; Coverage: 100%)
Gene name: CLIC4
Sequence domains: Glutathione S-transferase, N-terminal domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 73.19Å b: 86.05Å c: 73.38Å
α: 90° β: 112.99° γ: 90°
R-values:
R R work R free
0.216 0.216 0.262
Expression system: Escherichia coli BL21(DE3)