› 2day

Solution NMR

Solution structure of the RWD domain of human ring finger protein 25

Released:
DOI: 10.2210/pdb2day/pdb
PDB entry 2day coloured by chain, ensemble of 20 models, front view.
PDB entry 2day coloured by chain, ensemble of 20 models, side view.
PDB entry 2day coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Yoneyama M, Kigawa T, Sato M, Tochio N, Koshiba S, Inoue M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 ubiquitin-protein ligase RNF25 Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q96BH1 (Residues: 11-125; Coverage: 25%)
Gene name: RNF25
Sequence domains: RWD domain
Structure domains: Ubiquitin Conjugating Enzyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Cell free synthesis

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