› 2dci

Solution NMR

NMR structure of influenza HA fusion peptide mutant W14A in DPC in pH5

Released:
DOI: 10.2210/pdb2dci/pdb
PDB entry 2dci coloured by chain, ensemble of 33 models, front view.
PDB entry 2dci coloured by chain, ensemble of 33 models, side view.
PDB entry 2dci coloured by chain, ensemble of 33 models, top view.
Source organism: Influenza A virus (A/swine/Hong Kong/126/1982(H3N2))
Primary publication:
Fusion peptide of influenza hemagglutinin requires a fixed angle boomerang structure for activity.
Lai AL, Park H, White JM, Tamm LK
J Biol Chem 281 5760-70 (2006)
PMID: 16407195

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145671 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hemagglutinin HA2 chain Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 1.94 KDa
Source organism: Influenza A virus (A/swine/Hong Kong/126/1982(H3N2))
Expression system: Not provided
UniProt:
  • Canonical: P11134 (Residues: 330-349; Coverage: 4%)
Gene name: HA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: distance geometry
Expression system: Not provided

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Citations

16 review citations

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
White et al. (2008)
15 more

4 mentions without citation

Combined NMR and EPR spectroscopy to determine structures of viral fusion domains in membranes.
Tamm et al. (2007)
3 more