› 2dcv

Solution NMR

The solution structure of horseshoe crab antimicrobial peptide tachystatin b with the inhibitory cystine-knot motif

Released:
DOI: 10.2210/pdb2dcv/pdb
PDB entry 2dcv coloured by chain, ensemble of 20 models, front view.
PDB entry 2dcv coloured by chain, ensemble of 20 models, side view.
PDB entry 2dcv coloured by chain, ensemble of 20 models, top view.
Source organism: Tachypleus tridentatus
Primary publication:
The solution structure of horseshoe crab antimicrobial peptide tachystatin B with an inhibitory cystine-knot motif.
Fujitani N, Kouno T, Nakahara T, Takaya K, Osaki T, Kawabata S, Mizuguchi M, Aizawa T, Demura M, Nishimura S, Kawano K
J Pept Sci 13 269-79 (2007)
PMID: 17394123

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142981 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tachystatin-B1 Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.93 KDa
Source organism: Tachypleus tridentatus
UniProt:
  • Canonical: P0C1Z8 (Residues: 1-42; Coverage: 100%)
Sequence domains: Antimicrobial chitin binding protein tachystatin B
Structure domains: Omega-AgatoxinV

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing

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Citations

3 review citations

Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control.
Otero-González et al. (2010)
2 more