› 2dda

X-ray diffraction
2.25Å resolution

Crystal structure of pseudechetoxin from Pseudechis australis

Released:
DOI: 10.2210/pdb2dda/pdb
PDB entry 2dda coloured by chain, front view.
PDB entry 2dda coloured by chain, side view.
PDB entry 2dda coloured by chain, top view.
Source organism: Pseudechis australis
Primary publication:
Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domain.
Suzuki N, Yamazaki Y, Brown RL, Fujimoto Z, Morita T, Mizuno H
Acta Crystallogr D Biol Crystallogr 64 1034-42 (2008)
PMID: 18931410

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183819 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cysteine-rich venom protein pseudechetoxin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 211 amino acids
Theoretical weight: 23.76 KDa
Source organism: Pseudechis australis
UniProt:
  • Canonical: Q8AVA4 (Residues: 28-238; Coverage: 96%)
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand NA 4 x NA
Ligand FMT 6 x FMT
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P212121
Unit cell:
a: 60.303Å b: 61.594Å c: 251.686Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.203 0.259

Quick links

Citations

5 review citations

The role of cysteine-rich secretory proteins in male fertility.
Koppers et al. (2011)
4 more

7 mentions without citation

Cysteine-Rich Secretory Proteins (CRISPs) From Venomous Snakes: An Overview of the Functional Diversity in A Large and Underappreciated Superfamily.
Tadokoro et al. (2020)
6 more