› 2dhs

Solution NMR

Solution Structure of Nucleic Acid Binding Protein CUGBP1ab and its Binding Study with DNA and RNA

Released:
DOI: 10.2210/pdb2dhs/pdb
PDB entry 2dhs coloured by chain, ensemble of 7 models, front view.
PDB entry 2dhs coloured by chain, ensemble of 7 models, side view.
PDB entry 2dhs coloured by chain, ensemble of 7 models, top view.
Source organism: Homo sapiens
Entry authors: Xia YL, Jun KY, Zhu Q, Han XG, Zhang H, Timchenko L, Swanson M, Gao XL

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187791 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CUGBP Elav-like family member 1 Chain: A
Molecule details ›
Chain: A
Length: 187 amino acids
Theoretical weight: 21.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92879 (Residues: 1-187; Coverage: 39%)
Gene names: BRUNOL2, CELF1, CUGBP, CUGBP1, NAB50
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: simulated annealing molecular dynamics
Expression system: Escherichia coli BL21(DE3)

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