› 2dhz

Solution NMR

Solution Structure of the RA Domain in the Human Link Guanine Nucleotide Exchange Factor II (Link-GEFII)

Released:
DOI: 10.2210/pdb2dhz/pdb
PDB entry 2dhz coloured by chain, ensemble of 20 models, front view.
PDB entry 2dhz coloured by chain, ensemble of 20 models, side view.
PDB entry 2dhz coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Zhao C, Kigawa T, Yoneyama M, Koshiba S, Harada T, Watanabe S, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193765 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rap guanine nucleotide exchange factor-like 1 Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 12.78 KDa
Source organism: Homo sapiens
Expression system: Cell free synthesis
UniProt:
  • Canonical: Q9UHV5 (Residues: 314-420; Coverage: 16%)
Gene name: RAPGEFL1
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Cell free synthesis

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