› 2do6

Solution NMR

Solution structure of RSGI RUH-065, a UBA domain from human cDNA

Released:
DOI: 10.2210/pdb2do6/pdb
PDB entry 2do6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2do6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2do6 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Hamada T, Hirota H, Lin Y-J, Guntert P, Sato M, Koshiba S, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171599 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 ubiquitin-protein ligase CBL-B Chains: A, B
Molecule details ›
Chains: A, B
Length: 53 amino acids
Theoretical weight: 5.52 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13191 (Residues: 931-970; Coverage: 4%)
Gene names: CBLB, Nbla00127, RNF56

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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