› 2dp8

X-ray diffraction
2.5Å resolution

Carbohydrate recognition by lactoferrin: Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with trisaccharide at 2.5 A resolution

Released:
DOI: 10.2210/pdb2dp8/pdb
PDB entry 2dp8 coloured by chain, front view.
PDB entry 2dp8 coloured by chain, side view.
PDB entry 2dp8 coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Singh N, Sharma S, Singh TP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (5 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 345 amino acids
Theoretical weight: 37.66 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 361-705; Coverage: 50%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
4 bound ligands:
Ligand FE 1 x FE
Ligand CO3 1 x CO3
Ligand ZN 2 x ZN
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 63.082Å b: 50.437Å c: 65.79Å
α: 90° β: 107.53° γ: 90°
R-values:
R R work R free
0.19 0.184 0.2

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