› 2dqk

X-ray diffraction
1.93Å resolution

Crystal structure of the complex of proteinase K with a specific lactoferrin peptide Val-Leu-Leu-His at 1.93 A resolution

Released:
DOI: 10.2210/pdb2dqk/pdb
PDB entry 2dqk coloured by chain, front view.
PDB entry 2dqk coloured by chain, side view.
PDB entry 2dqk coloured by chain, top view.
Source organism: Parengyodontium album
Entry authors: Singh AK, Singh N, Sharma S, Dey S, Bhushan A, Singh TP

Function and Biology Details

Reaction catalysed: 
Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyzes peptide amides.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139282 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proteinase K Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 28.96 KDa
Source organism: Parengyodontium album
UniProt:
  • Canonical: P06873 (Residues: 106-384; Coverage: 76%)
Gene name: PROK
Sequence domains: Subtilase family
Structure domains: Peptidase S8/S53 domain
VLLH Chain: P
Molecule details ›
Chain: P
Length: 4 amino acids
Theoretical weight: 482 Da
Source organism: Parengyodontium album
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand NO3 1 x NO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P43212
Unit cell:
a: 68.313Å b: 68.313Å c: 108.407Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.152 0.187
Expression system: Not provided

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