› 2dt6

Solution NMR

Solution structure of the first SURP domain of human splicing factor SF3a120

Released:
DOI: 10.2210/pdb2dt6/pdb
PDB entry 2dt6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2dt6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2dt6 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP.
Kuwasako K, He F, Inoue M, Tanaka A, Sugano S, Güntert P, Muto Y, Yokoyama S
Structure 14 1677-89 (2006)
PMID: 17098193

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172293 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Splicing factor 3A subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15459 (Residues: 48-110; Coverage: 8%)
Gene names: SAP114, SF3A1
Sequence domains: Surp module
Structure domains: Surp module

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS, RESTRAINTED ENERGY MINIMIZATION
Expression system: Escherichia coli

Quick links

Citations

16 citation in other articles

Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling.
Lin-Moshier et al. (2013)
15 more

2 mentions without citation

Detailed close-ups and the big picture of spliceosomes.
Jurica MS. (2008)
1 more