› 2dww

X-ray diffraction
1.8Å resolution

Crystal structure of Bromodomain-containing protein 4

Released:
DOI: 10.2210/pdb2dww/pdb
PDB entry 2dww coloured by chain, front view.
PDB entry 2dww coloured by chain, side view.
PDB entry 2dww coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Padmanabhan B, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190195 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 13.64 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q9ESU6 (Residues: 347-460; Coverage: 8%)
Gene names: Brd4, Mcap
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
1 modified residue:
Ligand MSE 7 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P21212
Unit cell:
a: 73.891Å b: 57.779Å c: 33.588Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.186 0.245
Expression system: Not provided

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