› 2dyq

X-ray diffraction
3.1Å resolution

Crystal Structure of the C-terminal Phophotyrosine Interaction Domain of Human APBB3

Released:
DOI: 10.2210/pdb2dyq/pdb
PDB entry 2dyq coloured by chain, front view.
PDB entry 2dyq coloured by chain, side view.
PDB entry 2dyq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Nishino A, Saijo S, Kishishita S, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131988 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta A4 precursor protein-binding family B member 3 Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O95704 (Residues: 281-417; Coverage: 28%)
Gene names: APBB3, FE65L2
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P6222
Unit cell:
a: 82.292Å b: 82.292Å c: 104.871Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.256 0.254 0.298
Expression system: Not provided

Quick links