We've built a new version of this page with an interactive 3D viewer. Try it out in beta and help us improve:

› 2e0o

X-ray diffraction
2Å resolution

Function and Biology Details

Reaction catalysed: 
(1) an [RNA] containing cytidine + H2O = an [RNA]-3'-cytidine-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA].
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-139880 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chains: A, B
Molecule details ›
Chains: A, B
Length: 129 amino acids
Theoretical weight: 14.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07998 (Residues: 29-156; Coverage: 100%)
Gene names: RIB1, RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

2 bound ligands:
Ligand SO4 9 x SO4
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P6122
Unit cell:
a: 98.461Å b: 98.461Å c: 112.087Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.207 0.255
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Racemic protein crystallography.
Yeates et al. (2012)
3 more

2 mentions without citation

'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines.
Yamada et al. (2007)
1 more