› 2e1r

X-ray diffraction
3.15Å resolution

Structure of eEF2 in complex with a sordarin derivative

Released:
DOI: 10.2210/pdb2e1r/pdb
PDB entry 2e1r coloured by chain, front view.
PDB entry 2e1r coloured by chain, side view.
PDB entry 2e1r coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2.
Søe R, Mosley RT, Justice M, Nielsen-Kahn J, Shastry M, Merrill AR, Andersen GR
J Biol Chem 282 657-66 (2007)
PMID: 17082187

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152261 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

2 bound ligands:
Ligand SOD 1 x SOD
Ligand GDP 1 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7A
Spacegroup: P21212
Unit cell:
a: 116.86Å b: 158.77Å c: 60.31Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.22 0.27

Quick links

Citations

5 review citations

Oxidative Cyclization in Natural Product Biosynthesis.
Tang et al. (2017)
4 more

1 mention without citation

Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution.
Nguyen et al. (2016)