› 2e2s

Solution NMR

Solution structure of agelenin, an insecticidal peptide from the venom of Agelena opulenta

Released:
DOI: 10.2210/pdb2e2s/pdb
PDB entry 2e2s coloured by chain, ensemble of 20 models, front view.
PDB entry 2e2s coloured by chain, ensemble of 20 models, side view.
PDB entry 2e2s coloured by chain, ensemble of 20 models, top view.
Source organism: Allagelena opulenta
Primary publication:
Solution structure of agelenin, an insecticidal peptide isolated from the spider Agelena opulenta, and its structural similarities to insect-specific calcium channel inhibitors.
Yamaji N, Sugase K, Nakajima T, Miki T, Wakamori M, Mori Y, Iwashita T
FEBS Lett 581 3789-94 (2007)
PMID: 17644092

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151980 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
U2-agatoxin-Aop1a Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 3.83 KDa
Source organism: Allagelena opulenta
UniProt:
  • Canonical: P31328 (Residues: 1-35; Coverage: 100%)
Sequence domains: Toxin 7

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing

Quick links

Citations

4 citation in other articles

Unique bell-shaped voltage-dependent modulation of Na+ channel gating by novel insect-selective toxins from the spider Agelena orientalis.
Billen et al. (2010)
3 more

1 mention without citation

Classes, Databases, and Prediction Methods of Pharmaceutically and Commercially Important Cystine-Stabilized Peptides.
Islam et al. (2018)