› 2e3v

X-ray diffraction
1.95Å resolution

Crystal structure of the first fibronectin type III domain of neural cell adhesion molecule splicing isoform from human muscle culture lambda-4.4

Released:
DOI: 10.2210/pdb2e3v/pdb
PDB entry 2e3v coloured by chain, front view.
PDB entry 2e3v coloured by chain, side view.
PDB entry 2e3v coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Nishino A, Saijo S, Kishishita S, Chen L, Liu ZJ, Wang BC, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146665 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neural cell adhesion molecule 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 122 amino acids
Theoretical weight: 12.84 KDa
Source organism: Homo sapiens
Expression system: Cell-free protein synthesis
UniProt:
  • Canonical: P13591 (Residues: 510-619; Coverage: 13%)
Gene names: NCAM, NCAM1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

4 bound ligands:
Ligand PEG 3 x PEG
Ligand PGE 2 x PGE
Ligand BTB 2 x BTB
Ligand EDO 1 x EDO
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2, APS BEAMLINE 22-ID
Spacegroup: P31
Unit cell:
a: 55.378Å b: 55.378Å c: 118.83Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.182 0.211
Expression system: Cell-free protein synthesis

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