› 2e63

Solution NMR

Solution structure of the NEUZ domain in KIAA1787 protein

Released:
DOI: 10.2210/pdb2e63/pdb
PDB entry 2e63 coloured by chain, ensemble of 20 models, front view.
PDB entry 2e63 coloured by chain, ensemble of 20 models, side view.
PDB entry 2e63 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional characterization of the NHR1 domain of the Drosophila neuralized E3 ligase in the notch signaling pathway.
He F, Saito K, Kobayashi N, Harada T, Watanabe S, Kigawa T, Güntert P, Ohara O, Tanaka A, Unzai S, Muto Y, Yokoyama S
J Mol Biol 393 478-95 (2009)
PMID: 19683535

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188583 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuralized-like protein 4 Chain: A
Molecule details ›
Chain: A
Length: 170 amino acids
Theoretical weight: 18.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q96JN8 (Residues: 43-205; Coverage: 10%)
Gene names: KIAA1787, NEURL4
Sequence domains: Neuralized
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

5 review citations

Notch ligand ubiquitylation: what is it good for?
Weinmaster et al. (2011)
4 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)