› 2e6m

X-ray diffraction
2Å resolution

structure of mouse werner exonuclease domain

Released:
DOI: 10.2210/pdb2e6m/pdb
Model geometry
Fit model/data
PDB entry 2e6m coloured by chain, front view.
PDB entry 2e6m coloured by chain, side view.
PDB entry 2e6m coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Cho Y, Choi JM

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126707 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.4 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O09053 (Residues: 31-238; Coverage: 15%)
Gene name: Wrn
Sequence domains: 3'-5' exonuclease
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P212121
Unit cell:
a: 54.925Å b: 59.189Å c: 60.466Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.209 0.243
Expression system: Escherichia coli BL21(DE3)

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