› 2e9h

Solution NMR

Solution structure of the eIF-5_eIF-2B domain from human Eukaryotic translation initiation factor 5

Released:
DOI: 10.2210/pdb2e9h/pdb
PDB entry 2e9h coloured by chain, ensemble of 20 models, front view.
PDB entry 2e9h coloured by chain, ensemble of 20 models, side view.
PDB entry 2e9h coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Tomizawa T, Tochio N, Koshiba S, Watanabe S, Harada T, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157147 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 5 Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.49 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P55010 (Residues: 1-150; Coverage: 35%)
Gene name: EIF5
Sequence domains: Domain found in IF2B/IF5
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided

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