› 2e9s

X-ray diffraction
1.78Å resolution

human neuronal Rab6B in three intermediate forms

Released:
DOI: 10.2210/pdb2e9s/pdb
PDB entry 2e9s coloured by chain, front view.
PDB entry 2e9s coloured by chain, side view.
PDB entry 2e9s coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vellieux FM, Tcherniuk S, Garcia-Saez I, Kozielski F

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192570 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-6B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 171 amino acids
Theoretical weight: 19.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NRW1 (Residues: 13-174; Coverage: 78%)
Gene name: RAB6B
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
Ligand NO3 1 x NO3
Ligand MG 2 x MG
Ligand GDP 3 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P212121
Unit cell:
a: 60.808Å b: 65.185Å c: 108.672Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.231
Expression system: Escherichia coli BL21(DE3)

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