› 2ear

X-ray diffraction
3.1Å resolution

P21 crystal of the SR CA2+-ATPase with bound TG

Released:
DOI: 10.2210/pdb2ear/pdb
PDB entry 2ear coloured by chain, front view.
PDB entry 2ear coloured by chain, side view.
PDB entry 2ear coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors.
Takahashi M, Kondou Y, Toyoshima C
Proc Natl Acad Sci U S A 104 5800-5 (2007)
PMID: 17389383

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

1 bound ligand:
Ligand TG1 1 x TG1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P21
Unit cell:
a: 62.849Å b: 95.945Å c: 154.493Å
α: 90° β: 94.9° γ: 90°
R-values:
R R work R free
0.236 0.235 0.284

Quick links

Citations

14 review citations

P-type ATPases.
Palmgren et al. (2011)
13 more

9 mentions without citation

Multiscale Simulations of Biological Membranes: The Challenge To Understand Biological Phenomena in a Living Substance.
Enkavi et al. (2019)
8 more