› 2ebd

X-ray diffraction
2.1Å resolution

Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase III from Aquifex aeolicus VF5

Released:
DOI: 10.2210/pdb2ebd/pdb
PDB entry 2ebd coloured by chain, front view.
PDB entry 2ebd coloured by chain, side view.
PDB entry 2ebd coloured by chain, top view.
Source organism: Aquifex aeolicus VF5
Entry authors: Kumarevel TS, Kuramitsu S, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Acetyl-CoA + malonyl-[acyl-carrier-protein] = acetoacetyl-[acyl-carrier-protein] + CoA + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130467 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-ketoacyl-[acyl-carrier-protein] synthase III Chains: A, B
Molecule details ›
Chains: A, B
Length: 309 amino acids
Theoretical weight: 33.87 KDa
Source organism: Aquifex aeolicus VF5
Expression system: Escherichia coli
UniProt:
  • Canonical: O67185 (Residues: 1-309; Coverage: 100%)
Gene names: aq_1099, fabH
Sequence domains:
Structure domains: Peroxisomal Thiolase; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P212121
Unit cell:
a: 70.699Å b: 71.657Å c: 129.659Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.226
Expression system: Escherichia coli

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