› 2edi

Solution NMR

Solution structure of the UQ_con domain from human NEDD8-conjugating enzyme NCE2

Released:
DOI: 10.2210/pdb2edi/pdb
PDB entry 2edi coloured by chain, ensemble of 20 models, front view.
PDB entry 2edi coloured by chain, ensemble of 20 models, side view.
PDB entry 2edi coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Endo H, Izumi K, Yoshida M, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
S-[NEDD8-protein]-yl-[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-L-lysine = [E2 NEDD8-conjugating enzyme]-L-cysteine + N(6)-[NEDD8-protein]-yl-[cullin]-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NEDD8-conjugating enzyme UBE2F Chain: A
Molecule details ›
Chain: A
Length: 173 amino acids
Theoretical weight: 19.51 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q969M7 (Residues: 26-185; Coverage: 87%)
Gene names: NCE2, UBE2F
Sequence domains: Ubiquitin-conjugating enzyme
Structure domains: Ubiquitin Conjugating Enzyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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