› 2ee5

Solution NMR

Solution structure of the N-teruminus extended RhoGAP domain from human Rho GTPase activating protein 5 variant

Released:
DOI: 10.2210/pdb2ee5/pdb
PDB entry 2ee5 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ee5 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ee5 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Tomizawa T, Tochio N, Koshiba S, Watanabe S, Harada T, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171504 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho GTPase-activating protein 5 Chain: A
Molecule details ›
Chain: A
Length: 219 amino acids
Theoretical weight: 25.19 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13017 (Residues: 1245-1456; Coverage: 14%)
Gene names: ARHGAP5, RHOGAP5
Sequence domains: RhoGAP domain
Structure domains: Rho GTPase activation protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided

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