› 2ef0

X-ray diffraction
2Å resolution

Crystal structure of ornithine carbamoyltransferase from thermus thermophilus

Released:
DOI: 10.2210/pdb2ef0/pdb
PDB entry 2ef0 coloured by chain, front view.
PDB entry 2ef0 coloured by chain, side view.
PDB entry 2ef0 coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Karthe P, Kumarevel TS, Kuramitsu S, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-177989 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ornithine carbamoyltransferase Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 33.29 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SJ15 (Residues: 1-301; Coverage: 100%)
Gene names: TTHA1199, argF
Sequence domains:
Structure domains: Aspartate/ornithine carbamoyltransferase

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P63
Unit cell:
a: 77.385Å b: 77.385Å c: 79.132Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.2 0.236
Expression system: Escherichia coli

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