› 2eg9

X-ray diffraction
2.8Å resolution

Crystal structure of the truncated extracellular domain of mouse CD38

Released:
DOI: 10.2210/pdb2eg9/pdb
PDB entry 2eg9 coloured by chain, front view.
PDB entry 2eg9 coloured by chain, side view.
PDB entry 2eg9 coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Kukimoto-Niino M, Mishima C, Wakiyama M, Terada T, Shirouzu M, Hara-Yokoyama M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reactions catalysed: 
(1a) NADP(+) = 2'-phospho-cyclic ADP-ribose + nicotinamide
(1a) NAD(+) = cyclic ADP-ribose + nicotinamide
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157486 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 253 amino acids
Theoretical weight: 29.15 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P56528 (Residues: 48-288; Coverage: 79%)
Gene name: Cd38
Sequence domains: ADP-ribosyl cyclase
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21212
Unit cell:
a: 59.072Å b: 176.815Å c: 44.573Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.263 0.263 0.34
Expression system: Drosophila melanogaster

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