› 2egd

X-ray diffraction
1.8Å resolution

Crystal structure of human S100A13 in the Ca2+-bound state

Released:
DOI: 10.2210/pdb2egd/pdb
PDB entry 2egd coloured by chain, front view.
PDB entry 2egd coloured by chain, side view.
PDB entry 2egd coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of calcium-bound human S100A13 at pH 7.5 at 1.8 A resolution.
Imai FL, Nagata K, Yonezawa N, Nakano M, Tanokura M
Acta Crystallogr Sect F Struct Biol Cryst Commun 64 70-6 (2008)
PMID: 18259052

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-A13 Chains: A, B
Molecule details ›
Chains: A, B
Length: 98 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99584 (Residues: 1-98; Coverage: 100%)
Gene name: S100A13
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 39.774Å b: 59.287Å c: 77.624Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.234
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 citation in other articles

Stress-induced non-vesicular release of prothymosin-α initiated by an interaction with S100A13, and its blockade by caspase-3 cleavage.
Matsunaga et al. (2010)
3 more

4 mentions without citation

Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family.
Wheeler et al. (2016)
3 more