› 2ego

X-ray diffraction
1.8Å resolution

Crystal Structure of Tamalin PDZ Domain

Released:
DOI: 10.2210/pdb2ego/pdb
PDB entry 2ego coloured by chain, front view.
PDB entry 2ego coloured by chain, side view.
PDB entry 2ego coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation.
Sugi T, Oyama T, Muto T, Nakanishi S, Morikawa K, Jingami H
EMBO J 26 2192-205 (2007)
PMID: 17396155

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185901 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General receptor for phosphoinositides 1-associated scaffold protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 96 amino acids
Theoretical weight: 10.64 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8R4T5 (Residues: 96-189; Coverage: 24%)
Gene names: Grasp, Tamalin
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6B
Spacegroup: C2
Unit cell:
a: 111.282Å b: 30.034Å c: 80.111Å
α: 90° β: 132.328° γ: 90°
R-values:
R R work R free
0.235 0.235 0.267
Expression system: Escherichia coli BL21

Quick links

Citations

13 review citations

Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density.
Feng et al. (2009)
12 more

3 mentions without citation

Extracellular regulation of type IIa receptor protein tyrosine phosphatases: mechanistic insights from structural analyses.
Coles et al. (2015)
2 more