› 2egz

X-ray diffraction
1.75Å resolution

Crystal structure of the 3-dehydroquinate dehydratase from Aquifex aeolicus VF5

Released:
DOI: 10.2210/pdb2egz/pdb
PDB entry 2egz coloured by chain, front view.
PDB entry 2egz coloured by chain, side view.
PDB entry 2egz coloured by chain, top view.
Source organism: Aquifex aeolicus
Entry authors: Karthe P, Kumarevel TS, Ebihara A, Kuramitsu S, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
3-dehydroquinate = 3-dehydroshikimate + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130305 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-dehydroquinate dehydratase Chains: A, C
Molecule details ›
Chains: A, C
Length: 219 amino acids
Theoretical weight: 25 KDa
Source organism: Aquifex aeolicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O66440 (Residues: 1-219; Coverage: 100%)
Gene names: aq_021, aroD
Sequence domains: Type I 3-dehydroquinase
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:
Ligand TLA 2 x TLA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21
Unit cell:
a: 52.937Å b: 67.614Å c: 60.238Å
α: 90° β: 99.2° γ: 90°
R-values:
R R work R free
0.22 0.22 0.237
Expression system: Escherichia coli

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