› 2eia

X-ray diffraction
2.7Å resolution

X-RAY CRYSTAL STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS (EIAV) CAPSID PROTEIN P26

Released:
DOI: 10.2210/pdb2eia/pdb
PDB entry 2eia coloured by chain, front view.
PDB entry 2eia coloured by chain, side view.
PDB entry 2eia coloured by chain, top view.
Source organism: Equine infectious anemia virus
Primary publication:
Model for lentivirus capsid core assembly based on crystal dimers of EIAV p26.
Jin Z, Jin L, Peterson DL, Lawson CL
J Mol Biol 286 83-93 (1999)
PMID: 9931251

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159649 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein p26 Chains: A, B
Molecule details ›
Chains: A, B
Length: 206 amino acids
Theoretical weight: 23.39 KDa
Source organism: Equine infectious anemia virus
Expression system: Escherichia coli
UniProt:
  • Canonical: P69732 (Residues: 141-346; Coverage: 42%)
Gene name: gag
Sequence domains: Gag protein p24 C-terminal domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P6122
Unit cell:
a: 100.48Å b: 100.48Å c: 157.38Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.236 0.294
Expression system: Escherichia coli

Quick links

Citations

6 review citations

The structural biology of HIV assembly.
Ganser-Pornillos et al. (2008)
5 more

9 mentions without citation

Advances to tackle backbone flexibility in protein docking.
Harmalkar et al. (2021)
8 more