› 2elc

X-ray diffraction
1.55Å resolution

Crystal structure of TTHA1842 from Thermus thermophilus HB8

Released:
DOI: 10.2210/pdb2elc/pdb
PDB entry 2elc coloured by chain, front view.
PDB entry 2elc coloured by chain, side view.
PDB entry 2elc coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Shimizu K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177850 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anthranilate phosphoribosyltransferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 329 amino acids
Theoretical weight: 34.32 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SH88 (Residues: 1-329; Coverage: 100%)
Gene names: TTHA1842, trpD
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand GOL 12 x GOL
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: C2
Unit cell:
a: 165.319Å b: 72.913Å c: 141.263Å
α: 90° β: 125.21° γ: 90°
R-values:
R R work R free
0.187 0.187 0.202
Expression system: Escherichia coli BL21(DE3)

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