2eo2

Solution NMR

Solution structure of the insertion region (510-573) of FTHFS domain from mouse methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like protein

Released:
Source organism: Mus musculus
Entry authors: Kurosaki C, Nagashima T, Yoshida M, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-174870 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Monofunctional C1-tetrahydrofolate synthase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 7.9 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q3V3R1 (Residues: 510-573; Coverage: 7%)
Gene names: Fthfsdc1, Mthfd1l
Structure domains: Helicase, Ruva Protein; domain 3

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided