› 2epj

X-ray diffraction
1.7Å resolution

Crystal structure of glutamate-1-semialdehyde 2,1-aminomutase from Aeropyrum pernix

Released:
DOI: 10.2210/pdb2epj/pdb
PDB entry 2epj coloured by chain, front view.
PDB entry 2epj coloured by chain, side view.
PDB entry 2epj coloured by chain, top view.
Source organism: Aeropyrum pernix K1
Entry authors: Mizutani H, Kunishima N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(S)-4-amino-5-oxopentanoate = 5-aminolevulinate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195427 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate-1-semialdehyde 2,1-aminomutase Chain: A
Molecule details ›
Chain: A
Length: 434 amino acids
Theoretical weight: 46.53 KDa
Source organism: Aeropyrum pernix K1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y9I9 (Residues: 1-429; Coverage: 100%)
Gene names: APE_2299.1, hemL
Sequence domains: Aminotransferase class-III
Structure domains:

Ligands and Environments


Cofactor: Ligand PMP 1 x PMP
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: C2221
Unit cell:
a: 61.006Å b: 101.842Å c: 148.346Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.194
Expression system: Escherichia coli

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