› 2eqg

Solution NMR

Solution structure of the first A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3

Released:
DOI: 10.2210/pdb2eqg/pdb
PDB entry 2eqg coloured by chain, ensemble of 20 models, front view.
PDB entry 2eqg coloured by chain, ensemble of 20 models, side view.
PDB entry 2eqg coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Zhang HP, Hayahsi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149309 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
A20p50 Chain: A
Molecule details ›
Chain: A
Length: 49 amino acids
Theoretical weight: 5.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P21580 (Residues: 381-416; Coverage: 5%)
Gene names: OTUD7C, TNFAIP3
Sequence domains: A20-like zinc finger
Structure domains: CD2-Gal4

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links