› 2eqs

Solution NMR

Solution structure of the S1 RNA binding domain of human ATP-dependent RNA helicase DHX8

Released:
DOI: 10.2210/pdb2eqs/pdb
PDB entry 2eqs coloured by chain, ensemble of 20 models, front view.
PDB entry 2eqs coloured by chain, ensemble of 20 models, side view.
PDB entry 2eqs coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Suzuki S, Muto Y, Inoue M, Kigawa T, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172030 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent RNA helicase DHX8 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.37 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q14562 (Residues: 260-355; Coverage: 8%)
Gene names: DDX8, DHX8
Sequence domains: S1 RNA binding domain
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dyanamics, simulated annealing
Expression system: Not provided

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