› 2erx

X-ray diffraction
1.65Å resolution

Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate

Released:
DOI: 10.2210/pdb2erx/pdb
PDB entry 2erx coloured by chain, front view.
PDB entry 2erx coloured by chain, side view.
PDB entry 2erx coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Papagrigoriou E, Yang X, Elkins J, Niesen FE, Burgess N, Salah E, Fedorov O, Ball LJ, von Delft F, Sundstrom M, Edwards A, Arrowsmith C, Weigelt J, Doyle D

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188538 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTP-binding protein Di-Ras2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 172 amino acids
Theoretical weight: 19.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96HU8 (Residues: 5-176; Coverage: 86%)
Gene name: DIRAS2
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
Ligand PO4 2 x PO4
Ligand MG 2 x MG
Ligand GDP 2 x GDP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 55.041Å b: 74.931Å c: 85.691Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.163 0.162 0.188
Expression system: Escherichia coli

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