› 2esw

X-ray diffraction
2.01Å resolution

Atomic structure of the N-terminal SH3 domain of mouse beta PIX,p21-activated kinase (PAK)-interacting exchange factor

Released:
DOI: 10.2210/pdb2esw/pdb
PDB entry 2esw coloured by chain, front view.
PDB entry 2esw coloured by chain, side view.
PDB entry 2esw coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor.
Li X, Liu X, Sun F, Gao J, Zhou H, Gao GF, Bartlam M, Rao Z
Biochem Biophys Res Commun 339 407-14 (2006)
PMID: 16307729

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-190183 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho guanine nucleotide exchange factor 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 61 amino acids
Theoretical weight: 6.97 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9ES28 (Residues: 164-220; Coverage: 7%)
Gene names: Arhgef7, Kiaa0142, Pak3bp
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:
Ligand HG 6 x HG
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P3221
Unit cell:
a: 88.287Å b: 88.287Å c: 40.558Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.256 0.232 0.254
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

Cellular signaling for activation of Rho GTPase Cdc42.
Sinha et al. (2008)
4 other articles