› 2etc

X-ray diffraction
3.1Å resolution

Crystal structure of the ankyrin repeat domain of TRPV2

Released:
DOI: 10.2210/pdb2etc/pdb
PDB entry 2etc coloured by chain, front view.
PDB entry 2etc coloured by chain, side view.
PDB entry 2etc coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure of the N-terminal ankyrin repeat domain of the TRPV2 ion channel.
Jin X, Touhey J, Gaudet R
J Biol Chem 281 25006-10 (2006)
PMID: 16809337

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194386 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transient receptor potential cation channel subfamily V member 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 274 amino acids
Theoretical weight: 30.57 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9WUD2 (Residues: 62-326; Coverage: 35%)
Gene names: Sac2b, Trpv2, Vrl1
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 8-BM
Spacegroup: P212121
Unit cell:
a: 39.514Å b: 95.862Å c: 164.504Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.307 0.21 0.262
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

36 review citations

The transient receptor potential family of ion channels.
Nilius et al. (2011)
35 more

6 mentions without citation

A primer on ankyrin repeat function in TRP channels and beyond.
Gaudet R. (2008)
5 more