› 2ewo

X-ray diffraction
2.9Å resolution

X-ray structure of putative agmatine deiminase Q8DW17, Northeast Structural Genomics target SmR6.

Released:
DOI: 10.2210/pdb2ewo/pdb
PDB entry 2ewo coloured by chain, front view.
PDB entry 2ewo coloured by chain, side view.
PDB entry 2ewo coloured by chain, top view.
Source organism: Streptococcus mutans
Entry authors: Kuzin AP, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reaction catalysed: 
Agmatine + H(2)O = N-carbamoylputrescine + NH(3)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184252 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative agmatine deiminase Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 377 amino acids
Theoretical weight: 43.33 KDa
Source organism: Streptococcus mutans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8DW17 (Residues: 1-369; Coverage: 100%)
Gene names: SMU_264, aguA
Sequence domains: Porphyromonas-type peptidyl-arginine deiminase
Structure domains: L-arginine/glycine Amidinotransferase; Chain A

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 96 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P21
Unit cell:
a: 92.524Å b: 203.685Å c: 139.543Å
α: 90° β: 104.72° γ: 90°
R-values:
R R work R free
0.235 0.235 0.269
Expression system: Escherichia coli

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