› 2ezm

Solution NMR

SOLUTION NMR STRUCTURE OF CYANOVIRIN-N, RESTRAINED REGULARIZED MEAN COORDINATES

Released:
DOI: 10.2210/pdb2ezm/pdb
PDB entry 2ezm coloured by chain, front view.
PDB entry 2ezm coloured by chain, side view.
PDB entry 2ezm coloured by chain, top view.
Source organism: Nostoc ellipsosporum
Primary publication:
Solution structure of cyanovirin-N, a potent HIV-inactivating protein.
Bewley CA, Gustafson KR, Boyd MR, Covell DG, Bax A, Clore GM, Gronenborn AM
Nat Struct Biol 5 571-8 (1998)
PMID: 9665171

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160489 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyanovirin-N Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 11.02 KDa
Source organism: Nostoc ellipsosporum
UniProt:
  • Canonical: P81180 (Residues: 1-101; Coverage: 100%)
Sequence domains: CVNH domain
Structure domains: Cyanovirin-N

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing

Quick links

Citations

30 review citations

3D domain swapping: as domains continue to swap.
Liu et al. (2002)
29 more

29 mentions without citation

Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2.
Christy et al. (2021)
28 more