› 2f0a

X-ray diffraction
1.8Å resolution

Crystal Structure of Monomeric Uncomplexed form of Xenopus dishevelled PDZ domain

Released:
DOI: 10.2210/pdb2f0a/pdb
PDB entry 2f0a coloured by chain, front view.
PDB entry 2f0a coloured by chain, side view.
PDB entry 2f0a coloured by chain, top view.
Source organism: Xenopus laevis
Entry authors: Friedland N, Hung L-W, Cheyette B, Moon RT, Earnest TN

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric
homo tetramer
homo trimer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156299 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Segment polarity protein dishevelled homolog DVL-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 98 amino acids
Theoretical weight: 11 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: P51142 (Residues: 252-340; Coverage: 12%)
Gene names: dsh, dvl2
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

2 bound ligands:
Ligand CO 1 x CO
Ligand SO4 1 x SO4
1 modified residue:
Ligand MSE 20 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P61
Unit cell:
a: 89.834Å b: 89.834Å c: 82.471Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.214 0.253
Expression system: Escherichia coli

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