› 2f1v

X-ray diffraction
2.7Å resolution

Outer membrane protein OmpW

Released:
DOI: 10.2210/pdb2f1v/pdb
PDB entry 2f1v coloured by chain, front view.
PDB entry 2f1v coloured by chain, side view.
PDB entry 2f1v coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
The outer membrane protein OmpW forms an eight-stranded beta-barrel with a hydrophobic channel.
Hong H, Patel DR, Tamm LK, van den Berg B
J Biol Chem 281 7568-77 (2006)
PMID: 16414958

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
homo hexamer
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-141781 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Outer membrane protein W Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 197 amino acids
Theoretical weight: 21.7 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A915 (Residues: 22-212; Coverage: 100%)
Gene names: JW1248, b1256, ompW, yciD
Sequence domains: OmpW family
Structure domains: Porin

Ligands and Environments

1 bound ligand:
Ligand GOL 6 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P212121
Unit cell:
a: 118.666Å b: 118.776Å c: 118.519Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.293 0.292 0.314
Expression system: Escherichia coli

Quick links

Citations

13 review citations

The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.
Li et al. (2015)
12 more

11 mentions without citation

The structural biology of β-barrel membrane proteins: a summary of recent reports.
Fairman et al. (2011)
10 more