› 2f3a

Solution NMR

Solution structure of the LL-37-derived aurein 1.2 analog (LLAA) in membrane-mimetic micelles

Released:
DOI: 10.2210/pdb2f3a/pdb
PDB entry 2f3a coloured by chain, ensemble of 5 models, front view.
PDB entry 2f3a coloured by chain, ensemble of 5 models, side view.
PDB entry 2f3a coloured by chain, ensemble of 5 models, top view.
Source organism: synthetic construct
Primary publication:
NMR studies of aurein 1.2 analogs.
Li X, Li Y, Peterkofsky A, Wang G
Biochim Biophys Acta 1758 1203-14 (2006)
PMID: 16716252

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162685 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
aurein 1.2 analog Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.72 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments.
Wang et al. (2014)
1 more

2 mentions without citation

Interaction of aurein 1.2 and its analogue with DPPC lipid bilayer.
Sajjadiyan et al. (2017)
1 more