› 2f3n

X-ray diffraction
2.1Å resolution

Crystal Structure of the native Shank SAM domain.

Released:
DOI: 10.2210/pdb2f3n/pdb
PDB entry 2f3n coloured by chain, front view.
PDB entry 2f3n coloured by chain, side view.
PDB entry 2f3n coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
An architectural framework that may lie at the core of the postsynaptic density.
Baron MK, Boeckers TM, Vaida B, Faham S, Gingery M, Sawaya MR, Salyer D, Gundelfinger ED, Bowie JU
Science 311 531-5 (2006)
PMID: 16439662

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191643 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SH3 and multiple ankyrin repeat domains protein 3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 76 amino acids
Theoretical weight: 9.09 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9JLU4 (Residues: 1674-1740; Coverage: 4%)
Gene names: Prosap2, Shank3
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P65
Unit cell:
a: 104.715Å b: 104.715Å c: 40.188Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.206 0.251
Expression system: Escherichia coli BL21

Quick links

Citations

52 review citations

The postsynaptic architecture of excitatory synapses: a more quantitative view.
Sheng et al. (2007)
51 more